Mexico stunned Brazil 2-0, beat Ecuador 2-1 and played in cruise control in a 0-0 tie with Chile to wrap up the Group B title.
Their reward: Argentina or Paraguay.
Argentina last met Mexico in Leipzig, Germany, on June 24, 2006 and eliminated them from the World Cup with a 2-1 extra-time win.
Paraguay last met Mexico in Estadio Azteca in Mexico City on June 5, 2007 and beat Mexico 1-0, thus becoming just the second team to beat Mexico in Azteca since 1981.
Brazil, meanwhile, gets Chile in a quarterfinal matchup.
Still, Mexico coach Hugo Sanchez seems more worried about his own team than his opponents.
"Any team that faces Mexico will have to play their best in order to beat them because we are improving and are very concentrated."